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Article
A Nodule-Specific Protein Secretory Pathway Required for Nitrogen-Fixing Symbiosis
Science (2010)
  • Dong Wang, University of Massachusetts - Amherst
Abstract

The nitrogen-fixing symbiosis between Sinorhizobium meliloti and its leguminous host plant Medicago truncatula occurs in a specialized root organ called the nodule. Bacteria that are released into plant cells are surrounded by a unique plant membrane compartment termed a symbiosome. We found that in the symbiosis-defective dnf1 mutant of M. truncatula, bacteroid and symbiosome development are blocked. We identified the DNF1 gene as encoding a subunit of a signal peptidase complex that is highly expressed in nodules. By analyzing data from whole-genome expression analysis, we propose that correct symbiosome development in M. truncatula requires the orderly secretion of protein constituents through coordinated up-regulation of a nodule-specific pathway exemplified by DNF1.

Publication Date
February 26, 2010
Publisher Statement
This article was harvested from PubMed. doi: 10.1126/science.1184096
Citation Information
Dong Wang. "A Nodule-Specific Protein Secretory Pathway Required for Nitrogen-Fixing Symbiosis" Science Vol. 327 Iss. 5969 (2010)
Available at: http://works.bepress.com/dong_wang/2/