A method has been developed for preparative isolation of destruxins, a group of major insecticidal cyclodepsipeptides from culture broth of Metarhizium anisopliae. Prepurification of the crude extract by flash chromatography on silica gel followed by HPLC on reverse phase C18 Column using linear gradients of acetonitrile-water permitted the isolation of ten destruxins.
Preparative isolation of destruxins from Metarhizium anisopliae by high performance liquid chromatographyJournal of Liquid Chromatography
Citation InformationGupta, S., D.W. Roberts and J.A.A. Renwick. 1989. Preparative isolation of destruxins from Metarhizium anisopliae by high performance liquid chromatography. J. Liquid Chromatography 12: 383-395.