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Article
Magnetic resonance enterography in evaluation and management of children with Crohn's disease
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  • Sara Smolinski, MD, Baystate Health
  • Michael George, MD, Baystate Health
  • Abdulmalik Dredar, MD, Baystate Health
  • Christopher hayes, MD, Baystate Health
  • Dmitry Rakita, MD, Baystate Health
Document Type
Article, Peer-reviewed
Publication Date
8-1-2014
Abstract

The role of radiologic evaluation in Crohn's disease (CD) has undergone a recent paradigm shift in which the radiologist adds value to the multidisciplinary team by longitudinally assessing therapeutic response and identifying treatment-modifying subtypes, such as fibrostenotic or fistulizing disease. Magnetic resonance enterography (MRE) has become the primary imaging modality used. The combination of multiplanar, multiparametric, and multiphasic contrast-enhanced imaging with the high spatial resolution and very high tissue contrast of MR imaging allows for detailed evaluation of intra-abdominal pathology, without the risk of cumulative radiation exposure. MRE provides the benefit of a complete evaluation of mural, extramural, and even extraintestinal manifestations and complications of CD in a single examination. Cine motility sequences and diffusion-weighted imaging may further increase sensitivity and specificity. MRE represents an ideal imaging modality for initial evaluation, assessment of therapeutic response, and evaluation of complications in patients with CD.

Citation Information
Smolinski S, George M, Dredar A, Hayes C, Rakita D. Magnetic resonance enterography in evaluation and management of children with Crohn's disease. Semin Ultrasound CT MR. 2014 Aug;35(4):331-48.