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Article
Protein-passivated Fe3O4 nanoparticles: low toxicity and rapid heating for thermal therapy
Journal of Materials Chemistry
(2008)
Abstract
Thermotherapy is a promising technique for the minimally invasive elimination of solid tumors. Here we report the fabrication of protein -coated iron oxide NPs (12 nm core) for use as thermal therapeutic agents. These albumin-passivated NPs are stable under physiological conditions, with rapid heating and cell killing capacity upon alternating magnetic field (AMF) exposure. The mode of action is specific: no measurable cytotoxicity was observed for the particle without AMF or for AMF exposure without the particle.
Disciplines
Publication Date
February, 2008
Publisher Statement
DOI: 10.1039/B718745A
Citation Information
D. Joseph Jerry, Bappaditya Samanta, Haoheng Yan, Nicholas O. Fisher, et al.. "Protein-passivated Fe3O4 nanoparticles: low toxicity and rapid heating for thermal therapy" Journal of Materials Chemistry Vol. 18 (2008) Available at: http://works.bepress.com/djoseph_jerry/2/