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Article
Anticancer activities of Nigella sativa (Black Cumin)
African Journal of Traditional, Complementary and Alternative Medicines
  • Md. Asaduzzaman Khan
  • Hanchun Chen
  • Mousumi Tania
  • Dianzheng Zhang, Philadelphia College of Osteopathic Medicine
Document Type
Article
Publication Date
1-1-2011
Disciplines
Abstract
Nigella sativa has been used as traditional medicine for centuries. The crude oil and thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc. It is effective against cancer in blood system, lung, kidney, liver, prostate, breast, cervix, skin with much safety. The molecular mechanisms behind its anticancer role is still not clearly understood, however, some studies showed that TQ has antioxidant role and improves body's defense system, induces apoptosis and controls Akt pathway. Although the anti-cancer activity of N. sativa components was recognized thousands of years ago but proper scientific research with this important traditional medicine is a history of last 2~3 decades. There are not so many research works done with this important traditional medicine and very few reports exist in the scientific database. In this article, we have summarized the actions of TQ and crude oil of N. sativa against different cancers with their molecular mechanisms. © African Journal of Traditional, Complementary and Alternative Medicines.
Comments

This article was published in African Journal of Traditional, Complementary and Alternative Medicines, Volume 8, Issue 5 SUPPL., Pages 226-232.

The published version is available at http://dx.doi.org/10.4314/ajtcam.v8i5S.10.

Copyright © 2011 AJO.

Citation Information
Md. Asaduzzaman Khan, Hanchun Chen, Mousumi Tania and Dianzheng Zhang. "Anticancer activities of Nigella sativa (Black Cumin)" African Journal of Traditional, Complementary and Alternative Medicines Vol. 8 Iss. 5 SUPPL. (2011) p. 226 - 232
Available at: http://works.bepress.com/dianzheng_zhang/20/