Article
The VHL/HIF Axis in the Development and Treatment of Pheochromocytoma/Paraganglioma
Frontiers in Endocrinology
Document Type
Article
Publication Date
1-1-2020
Disciplines
Abstract
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from chromaffin cells in the adrenal medulla (PCCs) or extra-adrenal sympathetic or parasympathetic paraganglia (PGLs). About 40% of PPGLs result from germline mutations and therefore they are highly inheritable. Although dysfunction of any one of a panel of more than 20 genes can lead to PPGLs, mutations in genes involved in the VHL/HIF axis including
PubMed ID
33329393
Citation Information
Song Peng, Jun Zhang, Xintao Tan, Yiqiang Huang, et al.. "The VHL/HIF Axis in the Development and Treatment of Pheochromocytoma/Paraganglioma" Frontiers in Endocrinology Vol. 11 (2020) Available at: http://works.bepress.com/dianzheng_zhang/104/
This article was published in Frontiers in Endocrinology, Volume 11.
The published version is available at https://doi.org/10.3389/fendo.2020.586857.
Copyright © 2020 Peng, Zhang, Tan, Huang, Xu, Silk, Zhang, Liu and Jiang. CC BY 4.0.