"Anticoagulation therapy is a life-enhancing therapy for patients who are at risk for embolic events secondary to atrial ﬁbrillation, valve replacement, and other comorbidities. Clinicians are motivated to decrease the amount of time that patients are either under- or over-anticoagulated, common conditions that decrease patient safety at either extreme. The primary purpose of this descriptive study was to examine the relationship between personal life event factors as measured by Norbeck’s Life Events Questionnaire, core demographics such as age and income, and anticoagulation regulation. Although many factors affect anticoagulation therapy, the precise impact of life events, positive or negative, is unknown. The salient ﬁndings of this study (n 202) showed a small, though statistically signiﬁcant, inverse relationship (r 0.184, P .01) between negative life events and decreased time within therapeutic international normalized ratio. Total Life Event scores showed a statistically signiﬁcant inverse relationship (r 0.159, P .05) to international normalized ratio time within therapeutic level. Lower income was inversely associated with higher negative Life Event scores (r0.192, P .01). The ﬁndings demonstrate the need for strategies that address the potential impact of life events in conjunction with coexisting screening measures used in anticoagulation clinics. Implications for this study are limited by lack of methodology documenting concurrent social support factors and limitations of the research tool to reﬂect life event issues speciﬁc to outpatient seniors. (J Vasc Nurs 2005;23:105-111)"
Available at: http://works.bepress.com/diane_stuenkel/11/