Skip to main content
Article
Effect of acepromazine and butorphanol on halothane minimum alveolar concentration in ponies
Equine Veterinary Journal (1997)
  • Thomas J Doherty
  • Dennis R Geiser
  • Barton W Rohrbach, Dr., University of Tennessee - Knoxville
Abstract

The effect of i.v. acepromazine (0.05 mg/kg bwt), butorphanol (0.05 mg/kg bwt) and a combination of acepromazine and butorphanol on halothane minimum alveolar concentration (MAC) was determined in 7 mixed-breed ponies. Ventilation was controlled, and blood pressure and temperature were maintained within normal limits. Following the determination of baseline MAC, treatments were administered to each pony in a random manner. The control treatment was normal saline. The baseline halothane MAC for the control group was 0.910.04%, and no significant change occurred after saline administration. Acepromazine decreased the halothane MAC from 0.920.02% to 0.580.04%, and the combination of acepromazine and butorphanol, decreased halothane MAC 0.950.04% to 0.590.06%, a decrease of 36.9 and 37.8%, respectively. The difference between these 2 treatments was not significant. Butorphanol did not significantly change the mean group value for MAC.

Keywords
  • acepromazine anaesthesia butorphanol halothane neuroleptics pharmacology preanaesthetic medication horses acetylpromazine anesthesia preanesthetic medication Equus Equidae Perissodactyla mammals vertebrates Chordata animals ungulates eukaryotes
Disciplines
Publication Date
1997
Citation Information
Thomas J Doherty, Dennis R Geiser and Barton W Rohrbach. "Effect of acepromazine and butorphanol on halothane minimum alveolar concentration in ponies" Equine Veterinary Journal Vol. 29 Iss. 5 (1997)
Available at: http://works.bepress.com/dennis_geiser/8/