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Article
Effect of high arterial carbon dioxide tension on efficiency of immunoglobulin G absorption in calves
American Journal of Veterinary Research (1999)
  • J.J. Drewry
  • J.D. Quigley, III
  • Dennis R. Geiser, DVM, University of Tennessee - Knoxville
  • M.G. Welborn
Abstract

Arterial and venous blood samples were collected 1, 13, 25 and 37 h after birth from 48 Holstein calves and analysed for PaCO2 , PaO2 , pH and bicarbonate and base excess concentrations; venous samples were analysed for plasma IgG concentrations. On the basis of 1-h PaCO2 , 19 calves were assigned to non-respiratory acidosis (PaCO2 <50 mmHg) and 29 calves to respiratory acidosis (PaCO2 50 mmHg) groups. 12 calves in the respiratory acidosis group were untreated and 12 calves were given 5 min of assisted ventilation. All calves received between 1.8 and 2 litres of colostrum 2, 14, 26 and 38 h after birth. Plasma volume and apparent efficiency of IgG absorption (AEA) were determined 25 h after birth. Artificial ventilation had no effect on plasma IgG concentration or AEA. Lack of effect of 1-h PaCO2 on AEA and IgG concentration indicated that calves compensated for moderate acid-base imbalances associated with birth. Calves born with high PaCO2 achieved adequate plasma IgG concentrations if fed an adequate amount of high-quality colostrum early in life. The effect of artificial ventilation on PaCO2 was temporary and did not increase AEA.

Publication Date
1999
Citation Information
J.J. Drewry, J.D. Quigley, Dennis R. Geiser and M.G. Welborn. "Effect of high arterial carbon dioxide tension on efficiency of immunoglobulin G absorption in calves" American Journal of Veterinary Research Vol. 60 Iss. 5 (1999)
Available at: http://works.bepress.com/dennis_geiser/10/