End-tidal carbon dioxide tension (PETCO2) and arterial carbon dioxide tension (PaCO2) were determined and compared in isoflurane-anaesthetised spontaneously breathing newborn foals. End-tidal carbon dioxide and PaCO2 values increased with respect to time. Difference between values of PETCO2 and PaCO2 increased over time. End-tidal carbon dioxide tension was useful to predict changes in and was more closely correlated with PaCO2 early in the anaesthetic period (T 60 minutes). The dead space volume to tidal volume (Vd/Vt) ratio increased with respect to time, indicating increase in physiological dead space in isoflurane-anaesthetised foals. It was concluded that the increased difference between widening of the PETCO2 and PaSO2 values over time may have been attributable to hypoventilation and decreased pulmonary capillary perfusion of alveoli.
- Anaesthesia blood chemistry carbon dioxide Foals horse diseases isoflurane Newborn animals horses anesthesia Equus Equidae Perissodactyla mammals vertebrates Chordata animals ungulates eukaryotes
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