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Thyroid c-cell carcinoma in an African pygmy hedgehog (Atelerix albiventris).
Journal of Zoo and Wildlife Medicine (2002)
  • Debra L Miller, University of Tennessee, Knoxville
  • E. L. Styer
  • J. K. Stobaeus
  • T. M. Norton
A 3-yr-old African pygmy hedgehog (Atelerix albiventris) was submitted with dysphagia, weight loss, and tetraparesis. A palpable mass was found on the ventral neck. Histologic examination revealed replacement of the thyroid gland by a highly cellular, expansile, and infiltrative mass composed of lobules of polygonal cells separated by fine fibrovascular septa. Examination of ultrathin sections revealed tumor cells with few to many dense-core neuroendocrine granules, approximately 100-200 nm in diameter, and stromal amyloid. Immunohistochemical stains were positive for neuron-specific enolase. Only rare cells had positive immunohistochemical staining for calcitonin. Findings are consistent with a neuroendocrine tumor of C-cell origin. This is the first report of a C-cell carcinoma in a hedgehog.
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Citation Information
Debra L Miller, E. L. Styer, J. K. Stobaeus and T. M. Norton. "Thyroid c-cell carcinoma in an African pygmy hedgehog (Atelerix albiventris)." Journal of Zoo and Wildlife Medicine Vol. 33 Iss. 4 (2002)
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