Article
The anti-biofilm efficacy of copper and zinc doped borate bioactive glasses
Future Microbiology
(2024)
Abstract
Hospital-acquired infections (HAIs) are common in medical settings and can be difficult to treat because they often involve biofilms – communities of bacteria that are hard to eliminate with antibiotics. Our study examines the use of a biomaterials called borate bioactive glasses (BBGs) enhanced with copper and zinc, which are metals are known for killing bacteria. We tested these materials against common bacteria found in HAIs to determine if they could prevent and break down biofilms. Our experiments showed that these metal-enhanced glasses could significantly reduce bacterial growth within a few days in a various of clinically-relevant scenarios, making them a promising solution for controlling infections in clinical settings. This research could lead to new ways to prevent and treat infections resistant to standard treatments.
Disciplines
Publication Date
Fall September 13, 2024
DOI
https://doi.org/10.1080/17460913.2024.2398410
Citation Information
Sarah Fakher and David J. Westenberg. "The anti-biofilm efficacy of copper and zinc doped borate bioactive glasses" Future Microbiology (2024) Available at: http://works.bepress.com/david_westenberg/45/