Participation in Interpol is in the U.S. national interest. However, Interpol’s practice of allowing its members to transmit diffusions without systematic prior review by Interpol raises serious concerns. The U.S. should work with other democracies to reform Interpol’s diffusion system and require the U.S. National Central Bureau to report annually on information provided to or received from Interpol about U.S. citizens. Because many Interpol members are not law-abiding democracies, the U.S. should further limit the nations that can access data that it provides to Interpol, protect U.S. citizens and individuals with a U.S. nexus from baseless or politicized Interpol notices and diffusions, and emphasize that continued U.S. support for Interpol depends on Interpol’s scrupulous adherence to its 1956 constitution.