Direct observation of single protein molecules in aqueous solutionBiochemistry and Molecular Pharmacology Publications and Presentations
UMMS AffiliationDepartment of Biochemistry and Molecular Pharmacology; RNA Therapeutics Institute
Medical Subject HeadingsCarbocyanines; Diffusion; Microscopy, Fluorescence; Microscopy, Video; Sensitivity and Specificity; Solutions; Streptavidin; Time Factors; Water
AbstractSingle molecule tracking (SMT) by fluorescence video microscopy has matured to be a well established method in the last few years. In this report we demonstrate the imaging and tracking of single protein molecules in a phosphate/Hepes buffer with high sensitivity at frame rates of 350 Hz.
Related ResourcesLink to Article in PubMed
Citation InformationDavid Grunwald, Andreas Hoekstra, Thomas Dange, Volker Buschmann, et al.. "Direct observation of single protein molecules in aqueous solution" Vol. 7 Iss. 4 (2006) ISSN: 1439-4235 (Linking)
Available at: http://works.bepress.com/david_grunwald/17/