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Lymphoid Enhancing Factor 1 (Lef-1) overexpression in epithelial ovarian, fallopian tube and peritoneal cancer and associations with clinical factors
Proceedings in Obstetrics and Gynecology
  • Aine Clements, University of Iowa
  • David Engle, University of Iowa
  • Dawne Shelton, University of Iowa
  • Traci Neff, University of Iowa
  • Soo Park, University of Iowa
  • David Bender, University of Iowa
  • Amina Ahmed, University of Iowa
  • Koen De Geest, University of Iowa
  • Anna Button, University of Iowa
  • John F. Engelhardt, University of Iowa
  • Michael Goodheart
Peer Reviewed
0
Publication Date
7-28-2011
Abstract

Lef-1 mRNA levels were statistically elevated in cases of ovarian, fallopian tube or peritoneal cancer when compared to non-cancerous controls. Among cancer cases, levels of Lef-1 were statistically different between stage and histology. Lef-1 overexpression may be predictive of poor overall survival. These findings suggest that Lef-1 overexpression may contribute to ovarian, fallopian tube and peritoneal carcinogenesis, and that further investigation is warranted.

Keywords
  • LEF-1,
  • ovarian cancer,
  • fallopian tube cancer,
  • peritoneal cancer
Total Pages
2
Rights
Copyright © Aine Clements, David Engle, Dawne Shelton, Traci Neff, Soo Park, David Bender, Amina Ahmed, Koen De Geest, Anna Button, John F. Engelhardt, and Michael J. Goodheart, 2011.
Creative Commons License
Creative Commons Attribution 3.0
Citation Information
Aine Clements, David Engle, Dawne Shelton, Traci Neff, et al.. "Lymphoid Enhancing Factor 1 (Lef-1) overexpression in epithelial ovarian, fallopian tube and peritoneal cancer and associations with clinical factors" (2011) p. 1 - 2 ISSN: 2154-4751
Available at: http://works.bepress.com/david_bender/7/