Research has been conducted for a number of years at the NASA Langley Research Center to develop a supersonic combustion ramjet (scramjet) capable of propelling a vehicle at hypersonic speeds in the atmosphere or beyond. Recently, that research has been directed toward the optimization of the scramjet combustor, and in particular the efficiency of fuel-air mixing and reaction in the engine. This paper describes a numerical study of fuel-air mixing and reaction in a supersonic combustor, and discusses the analysis of a technique that was used to enhance the mixing processes and overall combustion efficiency in the flow. Based on the results of that study, conclusions are drawn regarding the applicability of the technique to enhance mixing in a scramjet combustor.