Skip to main content
Contribution to Book
Inflammasomes and danger signals in the immune system
Reference Module in Biomedical Research
  • Hsin-Chih Lai
  • Mufadhal Al-Kuhlani
  • David M. Ojcius, University of the Pacific
  • Matthew A. Pettengill
Document Type
Contribution to Book
Editor(s)
Michael J. Caplan
Description
The innate immune system has evolved to recognize both pathogen- and damage-associated molecular patterns (PAMPs and DAMPs), which represent conserved microbial structures or generic markers of stress or damage, respectively, and to generate an appropriate response. One such response is the production of the critical cytokines interleukin-1β and interleukin-18, which follows incorporation of PAMP and DAMP signals, and requires the activation of protein complexes termed inflammasomes to generate mature cytokines.
Find in WorldCat
https://www.worldcat.org/title/reference-module-in-biomedical-research/oclc/902812782&referer=brief_results
ISBN
978-0-12-801238-3
Publication Date
1-1-2014
Publisher
Elsevier
Keywords
  • ATP; Caspase; DAMP; HMGB1; Immunology; Inflammasome; Inflammation; Interleukin-1β; NLRP3; Nod-like receptors; PAMP; Toll-like receptors
Disciplines
Comments

DOI: 10.1016/B978-0-12-801238-3.00106-9

Citation Information
Hsin-Chih Lai, Mufadhal Al-Kuhlani, David M. Ojcius and Matthew A. Pettengill. "Inflammasomes and danger signals in the immune system" Amsterdam, NetherlandsReference Module in Biomedical Research (2014)
Available at: http://works.bepress.com/david-ojcius/6/