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Article
Alternative functions for the multifarious inflammasome
Biomedical Journal
  • Jan Martel, Chang Gung University
  • Hsin-Chih Lai, Chang Gung University
  • Yun-Fei Ko, Ming Chi University of Technology
  • John Ding-E. Young, Chang Gung University
  • David M. Ojcius, University of the Pacific
ORCiD
David M. Ojcius: 0000-0003-1461-4495
Document Type
Article
DOI
10.1016/j.bj.2016.06.001
Publication Date
6-1-2016
Abstract
The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.
Citation Information
Jan Martel, Hsin-Chih Lai, Yun-Fei Ko, John Ding-E. Young, et al.. "Alternative functions for the multifarious inflammasome" Biomedical Journal Vol. 39 Iss. 3 (2016) p. 183 - 187 ISSN: 2319-4170
Available at: http://works.bepress.com/david-ojcius/31/