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Article
Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells
PLoS One
  • Matthew A. Pettengill, University of California, Merced
  • Verissa W. Lam, University of California, Merced
  • Ikechukwu Ollawa, University of California, Merced
  • Camila Marques-da-Silva, University of California, Merced
  • David M. Ojcius, University of California, Merced
ORCiD
David M. Ojcius: 0000-0003-1461-4495
Document Type
Article
DOI
10.1371/journal.pone.0048456
Publication Date
10-30-2012
Abstract
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans. However, ivermectin has never been shown to be effective against bacterial pathogens. Here we show that ivermectin also inhibits infection of epithelial cells by the bacterial pathogen, Chlamydia trachomatis, at doses that could be envisioned clinically for sexually-transmitted or ocular infections by Chlamydia.
Comments
Article e48456
Citation Information
Matthew A. Pettengill, Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, et al.. "Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells" PLoS One Vol. 7 Iss. 10 (2012) p. 1 - 4 ISSN: 1932-6203
Available at: http://works.bepress.com/david-ojcius/143/