"Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion" by Levi B. Watkin

Article

Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion

UMass Center for Clinical and Translational Science Supported Publications

Levi B. Watkin, University of Massachusetts Medical School
Rabinarayan Mishra, University of Massachusetts Medical School
Anna Gil, University of Massachusetts Medical School
Nuray Aslan, University of Massachusetts Medical School
Dario Ghersi, University of Nebraska-Omaha
Katherine Luzuriaga, University of Massachusetts Medical School
Liisa K. Selin, University of Massachusetts Medical School

Link

UMMS Affiliation

Department of Pathology; Program in Molecular Medicine

Publication Date

2017-10-1

Document Type

Article

Disciplines

Abstract

Detection of unique, functionally influenza A/EBV crossreactive oligoclonal CD8 T-cell repertoires in rare individuals who remain EBV-seronegative into fourth decade of life suggests that T-cell crossreactivity dependent heterologous immunity may protect from EBV infection.

Keywords

CD8,
influenza,
Epstein Barr virus,
EBV,
memory,
crossreactive,
heterologous immunity,
UMCCTS funding

DOI of Published Version

10.1016/j.jaci.2017.05.037

Source

J Allergy Clin Immunol. 2017 Oct;140(4):1206-1210. doi: 10.1016/j.jaci.2017.05.037. Epub 2017 Jun 16. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

28629751

Citation Information

Levi B. Watkin, Rabinarayan Mishra, Anna Gil, Nuray Aslan, et al.. "Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion" Vol. 140 Iss. 4 (2017) ISSN: 0091-6749 (Linking)
Available at: http://works.bepress.com/dario-ghersi/27/