My remarks are divided into three sections. In the first section I discuss the current challenge and suggest areas in which ethics centers and the Society for Ethics Across the Curriculum may be able to help. I begin the second section with an observation about a problem and the implications of a proper understanding of the responsible conduct of research. I also discuss what I suspect are two significant missed opportunities in the programs that have been developed so far. I focus attention on the missed opportunities, since addressing them seems to me the best way to avoid the problem. In the third and final section I offer some prompts for discussion that, I hope, will help us find ways to make the most of the opportunities presented by the new NSF NIH requirements.