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Article
Synthesis of Substituted 2-Amino-Cyclobutanones
Synthetic Communications
  • Nicola Armoush, Loyola University Chicago
  • Preeti Syal
  • Daniel P. Becker, Loyola University Chicago
Document Type
Article
Publication Date
5-9-2008
Pages
1679-1687
Publisher Name
Taylor & Francis
Disciplines
Abstract

A series of weakly nucleophilic nitrogen derivatives including carbamates, amides, sulfonamides, and anilines were reacted with 1,2‐bis(trimethylsilyloxy)cyclobutene under acidic conditions to afford various substituted 2‐aminocyclobutanone derivatives 3a–i in modest to excellent yields.

Comments
This is an Author's Accepted Manuscript of an article published in Synthetic Communications, Volume 38, Issue 11, 2008 © Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/00397910801981110
Creative Commons License
Creative Commons Attribution-Noncommercial-No Derivative Works 3.0
Citation Information
Nicola Armoush, Preeti Syal and Daniel P. Becker. "Synthesis of Substituted 2-Amino-Cyclobutanones" Synthetic Communications Vol. 38 Iss. 11 (2008)
Available at: http://works.bepress.com/daniel_p_becker/85/