Skip to main content
Serotonin 5-HT4 Agonist Activity of a Series of Meso-Azanoradamantane Benzamides
Bioorganic & Medicinal Chemistry Letters
  • Daniel Becker, Loyola University Chicago
  • Roger Nosal
  • Clara I. Villamil
  • Gary Gullikson
Document Type
Publication Date
Publisher Name
A series of meso-amino(methyl)azanoradamantane benzamides has been prepared and evaluated for 5-HT4agonism activity in the rat tunica muscularis mucosae (TMM) assay. Compound 8i is the most potent 5-HT4agonist in the series, with an EC50 of 217 nM.
Author Posting © Elsevier, 1997. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Bioorganic & Medicinal Chemistry Letters, Volume 7, Issue 17, September 9, 1997.
Creative Commons License
Creative Commons Attribution-Noncommercial-No Derivative Works 3.0
Citation Information
Daniel Becker, Roger Nosal, Clara I. Villamil and Gary Gullikson. "Serotonin 5-HT4 Agonist Activity of a Series of Meso-Azanoradamantane Benzamides" Bioorganic & Medicinal Chemistry Letters Vol. 17 Iss. 1 (1997)
Available at: