|Present||Associate Professor, Western University ‐ Department of Obstetrics and Gynaecology|
|Present||Associate Professor and Assistant Chair, Western University ‐ Department of Physiology and Pharmacology|
|Present||Scientist, Lawson Health Research Institute ‐ Children's Health Research Institute (CHRI)|
Fetal Development, Metabolism, Pregnancy, IUGR, Liver Diseases and Disorders, Fetal Programming, Substance Use, Epigenetics, Children's Health, Endoplasmic Recticulum Stress, Fetal Health, Health Trajectories, In-Utero Environment, Metabolic Syndrome, Metabolic Syndrome, Reproductive Medicine, Cannabinoids, Cardiovascular Disease, Diabetes, and Placenta
|2022 - 2027||The adverse Impact of Prenatal Cannabinoid Exposure on Placental and Postnatal Cardiovascular Function: Can we Intervene?|
|Canadian Institutes for Health Research|
|Colleague(s): David Natale|
|2021 - 2026||Mitochondrial dysfunction: A major player in hepatic development, function, and senescence|
|Natural Science and Engineering Council of Canada|
|2019 - 2022||The Impact of Perinatal 9-tetrahydrocannabinol (9-THC) Exposure on Long-term Cardiovascular Function in the Offspring|
|Heart and Stroke Foundation Canada|
Honors and Awards
- Recipient of the Western Faculty Scholar Award (2022)
- Recipient of the LHRI Dr. Joseph Gilbert Contribution of the Year Award (2022)
- Recipient of the CHRI Scientist of the Year Award (2014)
- Recipient of the Perinatal Research Society Perkin-Elmer Early Career Award (2011)
- Recipient of the University of Waterloo Faculty of Science Alumni of Honour Award (2007)
- Recipient of the Endocrine Scholar Award (2006)
- Medical Physiology/P2
- Human Physiology (Physiology 3120)
- Fetal Physiology (Physiology 4700b)
|1997 - 2003||PhD, Western University ‐ Department of Physiology and Pharmacology|
|1992 - 1997||BSc (Honours Co-operative), University of Waterloo ‐ Biology|
Recent Works (25)
Delta-9-tetrahydrocannabinol increases vascular endothelial growth factor (VEGF) secretion through a ...
Reproductive Toxicology (2022)
While the effects of delta-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, have been studied extensively in the central nervous system, ...
Prenatal Exposure to Delta-9-tetrahydrocannabidinol (THC) Alters the Expression of miR-122-5p ...
International Journal of Molecular Sciences (2022)
As cannabis use during pregnancy increases, it is important to understand its effectson the developing fetus. Particularly, the long-term effects ...
Δ9-Tetrahydrocannabinol leads to endoplasmic reticulum stress and mitochondrial dysfunction in ...
Reproductive toxicology (Elmsford, N.Y.) (2019)
While studies have demonstrated that the main psychoactive component of cannabis, Δ9-tetrahydrocannabinol (Δ9-THC) alone induces placental insufficiency and fetal growth ...
Maternal nicotine exposure leads to decreased cardiac protein disulfide isomerase ...
Journal of applied toxicology : JAT (2017)
Smoking throughout pregnancy can lead to complications during gestation, parturition and neonatal development. Thus, nicotine replacement therapies are a popular ...
Contribution to Book
Maternal Undernutrition and Long-term Effects on Hepatic Function
Diet, Nutrition, and Fetal Programming: From the Womb to Adults (2017)
Undernutrition in utero, regardless of the source, can impair proper liver development leading to long-term metabolic dysfunction. Understanding the molecular ...
Contribution to Book
Perinatal Malnutrition and Epigenetic Regulation of Long-term Metabolism in the ...
The Handbook of Nutrition, Diet and Epigenetics (2017)
Maternal malnutrition in perinatal life can have long-lasting adverse effects on glucose and lipid homeostasis in the offspring, culminating in ...