1. Patch clamp studies on colonic tumor cell line T84 show the presence of chloride channels.
2. The channels are activated by forskolin, PGE2, or 8-Br-cAMP.
3. Single channel conductance was ca 40 pS at the reversal potential, increasing to 70 pS at +80mV and decreasing to 25 pS at −80 mV.
4. Relative permeabilities were I > Br > Cl > F.
Available at: http://works.bepress.com/dan_halm/47/