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Article
Antiviral Activity of Nucleoside Analogues Against SARS-Coronavirus (SARS-CoV)
Antiviral Chemistry and Chemotherapy
  • Chung K. Chu, University of Georgia
  • Srinivas Gadthula, University of Georgia
  • Xin Chen, University of Georgia
  • Hyunah Choo, University of Georgia
  • Sureyya Olgen, University of Georgia
  • Dale L. Barnard, Utah State University
  • Robert W. Sidwell, Utah State University
Document Type
Article
Publisher
International Medical Press
Publication Date
10-1-2006
Disciplines
Abstract

The recent outbreak of severe acute respiratory syndrome (SARS), which is an acute respiratory illness, is caused by newly discovered SARS coronavirus (SARS-CoV). Herein we describe the antiviral activity of several classes of nucleoside analogues evaluated against SARS-CoV in Vero 76 cells, some of which exhibited moderate activity.

Citation Information
Chu, C.K., Gadthula, S., Chen, X., Choo, H., Olgen, S., Sidwell, R.W. and Barnard, D.L 2006. Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV). Antiviral Chemistry and Chemotherapy, 17: 285-289.