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Characterization of Physical, Spectral and Thermal Properties of Biofield Treated 1,2,4-Triazole
Journal of Molecular Pharmaceutics & Organic Process Research (2015)
  • Dahryn Trivedi
Abstract
Triazoles are an important class of compounds used as core molecule for the synthesis of many pharmaceutical drugs. The objective of the present research was to investigate the influence of biofield treatment on physical, spectral and thermal properties of 1,2,4-triazole. The study was performed in two groups, control and treatment. The control group remained as untreated, and biofield treatment was given to treatment group. The control and treated 1,2,4-triazole were characterized by X-ray diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermo Gravimetric analysis (TGA), Surface area analyzer, and Fourier transform infrared (FT-IR) spectroscopy. XRD analysis revealed a decrease in unit cell volume of treated 1,2,4-triazole (662.08 10-24 cm3) as compared to control sample (666.34 10-24 cm3). Similarly, a decrease in molecular weight of treated 1,2,4-triazole (69.78 g/mol) with respect to control (70.23 g/mol) was observed. Additionally, a substantial decrease in crystallite size (G) was observed in treated 1,2,4-triazole by 16.34% with respect to control. DSC analysis showed a slight increase in melting temperature of treated 1,2,4-triazole (124.22°C) as compared to control (123.76°C). Moreover, a significant increase in latent heat of fusion was noticed in treated 1,2,4-triazole by 21.16% as compared to control sample. TGA analysis showed a significant increase in maximum thermal decomposition temperature (Tmax) of treated 1,2,4-triazole (213.40°C) as compared to control (199.68°C). Surface area analysis using BET showed a substantial increase in surface area of the treated compound by 13.52% with respect to control. However, FT-IR analysis showed no structural changes in treated 1,2,4-triazole with respect to control. Overall, the result showed significant alteration of physical and thermal properties of the treated 1,2,4-triazole with respect to control.
Keywords
  • Trivedi Effect,
  • The Trivedi Effect,
  • Mahendra Kumar Trivedi,
  • Mahendra Trivedi,
  • Biofield,
  • Biofield Treatment,
  • X-Ray Diffraction,
  • Differential Scanning Calorimetry,
  • Surface Area Analyzer,
  • Fourier Transform Infrared Spectroscopy,
  • Antifungal,
  • Antiinflammatory,
  • Chemotherapeutic Agents,
  • TGA-DTA,
  • Dta Thermogram of Triazole,
  • Surface Area Analysis of Triazole,
  • Pharmaceutical Compounds
Publication Date
August 31, 2015
DOI
10.4172/2329-9053.1000128
Citation Information
Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, et al. (2015) Characterization of Physical, Spectral and Thermal Properties of Biofield Treated 1,2,4-Triazole. J Mol Pharm Org Process Res 3: 128. doi:10.4172/2329-9053.1000128
Creative Commons license
Creative Commons License
This work is licensed under a Creative Commons CC_BY-NC-SA International License.