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Article
Advances in Biomolecule Analysis: FTMS of Macromolecules
Journal of the Iowa Academy of Science
  • Curtiss D. Hanson, University of Northern Iowa
  • Ira M. Simet, University of Northern Iowa
  • Suzanne R. Smith, University of Northern Iowa
Document Type
Research
Keywords
  • Fourier transform ion cyclotron resonance,
  • mass spectrometry of biomolecules,
  • ion trap design,
  • high mass analysis
Abstract
The development of Fourier transform ion cyclotron resonance (FT-ICR) as an analytical technique has opened new avenues to the analysis of high molecular weight biomolecules. Because mass analysis is based on a detection of a frequency, it is possible to obtain high resolution mass measurements without sacrificing sensitivity. The unique ability to analyze high mass ions is based in the design of a passive ExB ion trap. Although in the past, field inhomogeneities have limited this technique, recent developments in both trap designs and excitation techniques have resulted in major improvements in both sensitivity and resolution.
Original Publication Date
1-1-1993
Publication Date
March 1993
Copyright
© Copyright 1993 by the Iowa Academy of Science, Inc.
Language
EN
File Format
application/pdf
Citation Information
Curtiss D. Hanson, Ira M. Simet and Suzanne R. Smith. "Advances in Biomolecule Analysis: FTMS of Macromolecules" Journal of the Iowa Academy of Science Vol. 100 Iss. 1 (1993) p. 1 - 8
Available at: http://works.bepress.com/curtiss-hanson/6/