This article presents a conceptual framework linking perspectives from migration and environment with rural livelihoods and interactional community research in the context of rural out-migration and environmental changes in developing countries. Household livelihoods and community interaction comprise two core mediating factors between rural out-migration and rural environmental outcomes. Developing an interdisciplinary conceptual framework is an important way to advance migration and environment research that is built on knowledge from a variety of disciplines. By building linkages across different research fields, our conceptual framework provides an overall picture of the relevant mechanisms through which out-migration affects the rural environment. The framework has implications for theory, methodology, and rural environment and development policy.