Loss of heterozygosity occurs via mitotic recombination in Trp53+/- mice and associates with mammary tumor susceptibility of the BALB/c strain.All Scholarly Works
Document TypeArticle, Peer-reviewed
AbstractLoss of heterozygosity (LOH) occurs commonly in cancers causing disruption of tumor suppressor genes and promoting tumor progression. BALB/c-Trp53() mice are a model of Li-Fraumeni syndrome, exhibiting a high frequency of mammary tumors and other tumor ty
Citation InformationCancer Res 2004 Aug 1;64(15):5140-7.