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About Christopher T. Calderone

Calderone’s research focuses on the enzymology of natural product biosynthesis. Natural products are a rich source of valuable compounds that include antibiotics, anticancer agents, and other therapeutics. However, it is often difficult or impossible to modify the structures of natural products to increase their effectiveness or lower their toxicity. By increasing our understanding of the pathways by which natural products are generated, the ultimate goal of Calderone’s research is to allow the engineering of modified products with desired properties. Calderone was recently awarded a Dreyfus Foundation Faculty Start-Up Award in support of these efforts.
BS, University of Chicago; MPhil, Cambridge University; PhD, Harvard University; Postdoc at Harvard Medical School
Calderone has been teaching at Macalester since 2008.

Curriculum Vitae

Research Interests

Enzymology, Natural products, Biosynthesis, Secondary metabolism, and Protein biochemistry

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Honors and Awards

  • Dreyfus Foundation Faculty Start-Up Award


  • Biochemistry I
  • Biochemistry II
  • Cell Biology and Genetics Lab

Selected Recent Publications (3)

Presentations (4)