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Selected Works of Christina B Cooley
Article
Beyond Cell Penetrating Peptides: Designed Molecular Transporters
Drug Discovery Today: Technologies (2012)
  • Paul A Wender
  • Christina B Cooley, Stanford University
  • Erika I Geihe
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Abstract

Inspired originally by peptides that traverse biological barriers, research on molecular transporters has since identified the key structural requirements that govern cellular entry, leading to new, significantly more effective and more readily available agents. These new drug delivery systems enable or enhance cellular and tissue uptake, can be targeted and provide numerous additional advantages of significance in imaging, diagnostics and therapy.

Keywords
  • arginine derivative,
  • cell penetrating peptide,
  • cyclosporin A,
  • dendrimer,
  • doxycycline,
  • guanidine,
  • neomycin,
  • clinical trial,
  • diagnosis,
  • drug delivery system,
  • imaging,
  • therapy
Disciplines
Publication Date
Spring 2012
Citation Information
Wender, P. A., Cooley, C. B., & Geihe, E. I. (2012). Beyond cell penetrating peptides: Designed molecular transporters. Drug Discovery Today: Technologies, 9, e49-e55. doi: 10.1016/j.ddtec.2011.07.004