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Presentation
Big Data Analysis of Drug Induced Hypersensitivity and Anaphylaxis Reactions in Clinical Cancer Trials
Journal of Allergy and Clinical Immunology
  • Christina Eldredge, University of South Florida
  • Arun Singavi, Medical College of Wisconsin
  • Cesar Lam, H Lee Moffitt Cancer Center
  • Joel Gallagher, Allergy and Asthma Center of North Carolina
  • Jake Luo, University of Wisconsin
Document Type
Presentation
Publication Date
3-1-2018
Keywords
  • Cancer,
  • Clinical trials,
  • Data management,
  • Data processing,
  • Data analysis,
  • Anaphylaxis,
  • Studies,
  • Hypersensitivity
Digital Object Identifier (DOI)
https://doi.org/10.1016/j.jaci.2017.12.279
Abstract

The dataset, which included study name, medical condition, intervention, arm titles, and adverse drug reactions, was queried for drug hypersensitivity reactions using the key terms: hypersensitivity, allergic reaction, allergy, anaphylaxis, allergic dermatitis, and drug hypersensitivity. Results Preliminary population analysis of 425 of the 1605 qualifying clinical trials from this dataset revealed 3,013 adverse drug hypersensitivity reactions of 118,159 patients at risk for HSRs (2.5% incidence).

Citation / Publisher Attribution

Journal of Allergy and Clinical Immunology, v. 121, issue 2, p. AB87

Citation Information
Christina Eldredge, Arun Singavi, Cesar Lam, Joel Gallagher, et al.. "Big Data Analysis of Drug Induced Hypersensitivity and Anaphylaxis Reactions in Clinical Cancer Trials" Journal of Allergy and Clinical Immunology Vol. 141 Iss. 2 (2018) p. AB87
Available at: http://works.bepress.com/christina-eldredge/13/