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Article
A randomized trial of heparin and saline for maintaining intravenous locks in neonates
Journal of the Society of Pediatric Nurses
  • J. Heilskov
  • Charmaine Kleiber, University of Iowa
  • K. Johnson
  • J. Miller
Document Type
Article
Peer Reviewed
1
Publication Date
7-1-1998
NLM Title Abbreviation
J Soc Pediatr Nurs
PubMed ID
9743925
DOI of Published Version
10.1111/j.1744-6155.1998.tb00216.x
Abstract

PURPOSE: To determine the effects of saline, heparin 2 units (U) per ml saline, and heparin 10 U/ml saline flush solutions on the duration of intravenous (i.v.) locks and the incidence of i.v. infiltration in neonates. DESIGN: Randomized double-blind experiment. SETTING: Tertiary-care nursery. PARTICIPANTS: Neonates (N = 90) hospitalized at birth in the intensive, intermediate care, or newborn units. MAIN OUTCOME MEASURES: Total hours from the time the i.v. was inserted to the time the i.v. was removed; hours from the time the i.v. was first flushed to the time the i.v. was removed; number of i.vs. removed because of infiltration. RESULTS: No statistical or clinical differences between the three groups for duration of i.v. nor for incidence of complications. CONCLUSIONS: The use of heparin in i.v. lock flush solution did not affect the duration of i.v. locks nor the incidence of infiltration in neonates.

Keywords
  • Anticoagulants/therapeutic use,
  • Catheterization,
  • Peripheral/methods,
  • Double-Blind Method,
  • Female,
  • Heparin/therapeutic use,
  • Humans,
  • Infant,
  • Newborn,
  • Infusions,
  • Intravenous/methods,
  • Male,
  • Neonatal Nursing,
  • Sodium Chloride/therapeutic use
Journal Article Version
Version of Record
Published Article/Book Citation
Journal of the Society of Pediatric Nurses, 3:3 (1998) pp.111-116.
Rights
Copyright © Wiley, 1998. Posted by permission.
Disciplines
Citation Information
J. Heilskov, Charmaine Kleiber, K. Johnson and J. Miller. "A randomized trial of heparin and saline for maintaining intravenous locks in neonates" Journal of the Society of Pediatric Nurses Vol. 3 Iss. 3 (1998) p. 111 - 116 ISSN: 1088-145X
Available at: http://works.bepress.com/charmaine_kleiber/61/