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The Limits of Consent: A Socio-ethical Approach to Human Subject Research in Medicine
  • Oonagh Corrigan, University of Plymouth
  • John McMillan, University of Hull
  • Kathleen Liddell, University of Cambridge
  • Martin Richards, University of Cambridge
  • Charles Weijer, The University of Western Ontario

Since its inception as an international requirement to protect patients and healthy volunteers taking part in medical research, informed consent has become the primary consideration in research ethics. Despite the ubiquity of consent, however, scholars have begun to question its adequacy for contemporary biomedical research. This book explores this issue, reviewing the application of consent to genetic research, clinical trials, and research involving vulnerable populations. For example, in genetic research, information obtained from an autonomous research participant may have significant bearing on the interests of family members who have not consented to the study. This casts doubt on the adequacy of consent for such studies. This book also questions the assumptions that informed consent is essential and that it satisfactorily protects the principle of individual autonomy. It reviews recent empirical studies that challenge the possibility of truly informed consent and highlights the extent to which consent is governed by social norms and expectations. It also investigates how consent might be of secondary importance in some circumstances, for example when a research project appears to protect a public or community interest.

  • medical research,
  • consent,
  • biomedical research,
  • genetic research,
  • clinical trials,
  • vulnerable populations,
  • informed consent,
  • individual autonomy
Publication Date
Publisher Statement
Dr. Charles Weijer was a co-editor of this book.
Citation Information
Oonagh Corrigan, John McMillan, Kathleen Liddell, Martin Richards, et al.. The Limits of Consent: A Socio-ethical Approach to Human Subject Research in Medicine. (2009)
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