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Central IRBs: Enhanced Protections for Research Participants [English and Spanish versions]
Psychiatry Information in Brief
  • Ekaterina Pivovarova, University of Massachusetts Medical School
  • Charles W. Lidz, University of Massachusetts Medical School
Publication Date
Document Type
Research in the Works
A Spanish translation of this publication is available for download under "Additional Files" below. Institutional Review Boards (IRBs) play a critical role in research, and assure safety and fairness to participants enrolled in research studies. Multisite studies are often reviewed by multiple IRBs (an IRB review at each site participating in the study), which can slow down study approval, result in duplication of effort, and occasionally produce contradictory decisions by different IRBs. To address these problems, the federal government has promoted the use of single IRBs (referred to as Central IRBs or CIRBs), where a single IRB is responsible for the review of all sites where the research study is conducted. The National Institutes of Health (NIH) has recently announced that beginning in 2017 all research conducted at multiple sites must be reviewed by a CIRB. This CIRB process is new and requires careful study to understand its pitfalls and benefits. As such, UMass Medical School and Columbia University received a (NIH) grant to study how different institutions conduct reviews of research involving multiple sites.
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Creative Commons Attribution-Noncommercial-Share Alike 3.0
  • IRBs,
  • Ethics in Research,
  • Central IRBs,
  • Institutional Review Boards,
  • Spanish
Citation Information
Ekaterina Pivovarova and Charles W. Lidz. "Central IRBs: Enhanced Protections for Research Participants [English and Spanish versions]" (2016)
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