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Comparison of outcomes research with clinical trials using preexisting data
Quantitative Health Sciences Publications and Presentations
  • John G. Canto, University of Alabama
  • Catarina I. Kiefe, University of Massachusetts Medical School
  • O. Dale Williams, University of Alabama
  • Hal V. Barron, University of California
  • William J. Rogers, University of Alabama
UMMS Affiliation
Department of Quantitative Health Sciences
Document Type
Medical Subject Headings
Bias (Epidemiology); *Cardiology; Causality; Cohort Studies; Confounding Factors (Epidemiology); Data Collection; *Databases, Factual; Ethics, Medical; *Health Services Research; Humans; *Outcome Assessment (Health Care); *Randomized Controlled Trials as Topic; Research Design

Outcomes research using analysis of preexisting data is a relatively new field with the potential to improve the quality and effectiveness of medical care, and may provide a useful complement to randomized studies. Motivated by the growth of this research in the cardiovascular literature, this review offers a framework to identify the core concepts of outcomes research from database analyses by comparing and contrasting it with the randomized clinical trial.

Rights and Permissions
Citation: Am J Cardiol. 1999 Oct 15;84(8):923-7, A6.
Related Resources
Link to Article in PubMed
Citation Information
John G. Canto, Catarina I. Kiefe, O. Dale Williams, Hal V. Barron, et al.. "Comparison of outcomes research with clinical trials using preexisting data" Vol. 84 Iss. 8 (1999) ISSN: 0002-9149 (Linking)
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