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Article
Neighborhood characteristics and components of the insulin resistance syndrome in young adults: the coronary artery risk development in young adults (CARDIA) study
Quantitative Health Sciences Publications and Presentations
  • Ana V. Diez-Roux, University of Michigan
  • David R. Jacobs, University of Minnesota
  • Catarina I. Kiefe, University of Massachusetts Medical School
UMMS Affiliation
Department of Quantitative Health Sciences
Date
10-29-2002
Document Type
Article
Medical Subject Headings
Adolescent; Adult; African Continental Ancestry Group; Cardiovascular Diseases; Cross-Sectional Studies; European Continental Ancestry Group; Female; Humans; Insulin Resistance; Male; Metabolic Syndrome X; Risk Factors; Sex Characteristics; United States
Abstract
OBJECTIVE: To examine associations of neighborhood characteristics with six components of the insulin resistance syndrome (IRS) in young adults. RESEARCH DESIGN AND METHODS: Cross-sectional data from the Coronary Artery Risk Development in Young Adults (CARDIA) Study were used to examine associations of neighborhood characteristics with the IRS in 3,093 nondiabetic adults aged 28-40 years. Measures of BMI, fasting HDL cholesterol, triglycerides, insulin, glucose, and systolic blood pressure were combined into an IRS score. U.S. Census-derived neighborhood characteristics were summarized into a neighborhood socioeconomic score, with an increasing score signifying increasing socioeconomic advantage. RESULTS: Among white men and women, the IRS score was inversely related to neighborhood socioeconomic score. Neighborhood characteristics remained associated with the IRS score after controlling for personal income and education (adjusted mean differences for 95th vs. 5th percentile of neighborhood score: -0.24 standard deviation units [SE = 0.12] in men and -0.56 standard deviation units [SE = 0.10] in women). Among black participants, neighborhood score was inversely associated with IRS score in persons of high income and education (mean differences 95th vs. 5th percentile -0.54 [SE 0.26] in men and -0.52 [SE 0.26] in women) but positively associated or not associated with IRS score in persons of low income and education (mean differences 0.60 [SE 0.21] in men and 0.00 [SE 0.16] in women). CONCLUSIONS: The IRS score is associated with neighborhood characteristics as early as young adulthood. Features of residential environments may be related to the development of insulin resistance.
Rights and Permissions
Citation: Diabetes Care. 2002 Nov;25(11):1976-82.
Related Resources
Link to Article in PubMed
Citation Information
Ana V. Diez-Roux, David R. Jacobs and Catarina I. Kiefe. "Neighborhood characteristics and components of the insulin resistance syndrome in young adults: the coronary artery risk development in young adults (CARDIA) study" Vol. 25 Iss. 11 (2002) ISSN: 0149-5992 (Linking)
Available at: http://works.bepress.com/catarina_kiefe/153/