I am an applied biostatistician with diverse research interests. These currently include a randomized trial of needle exchange for drug abusers, application of the expectation-maximization (EM) algorithm to analyses of neurophysiological data, the use of complex survey methodology to adjust for missingness in analyses of surveillance data, and analysis of unrecognized vertebral fractures in the National Hospital Discharge Survey data base. General interests are in the area of clinical trials methodology, particularly the issues of adjustment for missing data, meta-analysis, and interim power considerations.