|2016 - Present||Assistant Professor, University of the Pacific ‐ Thomas J. Long School of Pharmacy and Health Sciences|
|2009 - 2016||Assistant Professor, Virginia Commonwealth University|
|2006 - 2009||Postdoctoral Fellow/Research Associate, University of Chicago|
|2002 - 2006||Research Associate, Duke University ‐ Medical Center|
|2002 - 2005||Visiting Researcher, Marine Biological Laboratories|
|2000 - 2002||International Visiting Scholar, Texas Tech University Health Sciences Center|
drug-protein interaction, voltage-sensing mechanisms, membrane proteins, voltage-gated channels, pharmacology, bioelectrical signals, physiology, pathophysiology, medicinal chemistry, fluorescence spectroscopy, stochastic modeling, patch-clamp electrophysiology, fluorescence microscopy, electrophysiology, confocal fluorescence microscopy, cut-open voltage clamp, biophysics, neurobiology, brain physiology, ion channels, membrane biophysics, PTEN, fluorescence, calcium imaging, enzyme activity, patch clamp recording, neurotransmission, fluorescence imaging, ion channel gating, calcium image, molecular electrophysiology, voltage-sensitive dye imaging, voltage-gated potassium channels, and phosphatases
Honors and Awards
- 2013-2015 KL2 Scholar. Center for Clinical and Translational Research. VCU – NIH – NCATS
- 2012 Keystone Symposia Early Career Investigator Travel Award. Keystone Symposia Conference, “Synapses and Circuits: From Formation to Disease.”
- 2008 Carl Storm Fellowship. Gordon Research Conference
- 2003 Grant. National Center for Supercomputing Applications. Teragrid. Proposal: “Activity of Ryanodine Receptor during Calcium Release”
- 2003 Grass Fellowship in Neuroscience. Grass Foundation, Braintree-Woods Hole, MA
- 2000 Fellowship. V Escuela Latinoamericana de Neurociencias. Montevideo, Uruguay
- 1998-1999 Fellowship. Instituto Venezolano de Investigaciones Científicas. Caracas, Venezuela
- 1998 Defended with honor. B.S. Thesis. Advisor: Dr. Ariel L.M. Escobar
- PHRM122 - Physiology and Pathophysiology I
- PHRM135 - Pharmacology and Medicinal Chemistry I
|2006 - 2009||Postdoctoral Fellow, Biophysics, University of Chicago|
|2002 - 2006||Postdoctoral Fellow, Neurobiology, Duke University|
|2004||Ph.D., Physiology and Biophysics, Instituto Venezolano de Investigaciones Científicas|
|1998||B.S., Biology, Universidad Central de Venezuela|
Department of Physiology and Pharmacology
Thomas J. Long School of Pharmacy and Health Sciences
University of the Pacific
3601 Pacific Avenue
Stockton, CA 95211
Journal articles written by Dr. Carlos A. Villalba-Galea.
IKs channels open slowly because KCNE1 accessory subunits slow the ...
Proceedings of the National Academy of Sciences of the United States of America (2013)
Human I(Ks) channels activate slowly with the onset of cardiac action potentials to repolarize the myocardium. I(Ks) channels are composed ...
A human phospholipid phosphatase activated by a transmembrane control module
Journal of Lipid Research (2012)
In voltage-sensitive phosphatases (VSPs), a transmembrane voltage sensor domain (VSD) controls an intracellular phosphoinositide phosphatase domain, thereby enabling immediate initiation ...
Controlling the activity of a phosphatase and tensin homolog (PTEN ...
The Journal of Biological Chemistry (2011)
The recently discovered voltage-sensitive phosphatases (VSPs) hydrolyze phosphoinositides upon depolarization of the membrane potential, thus representing a novel principle for ...
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP
The Journal of General Physiology (2009)
The Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP) shares high homology with the phosphatidylinositol phosphatase enzyme known as PTEN (phosphatase and ...
Developmental changes of intracellular Ca2+ transients in beating rat hearts
American Journal of Physiology: Heart and Circulatory Physiology (2004)
Postnatal maturation of the rat heart is characterized by major changes in the mechanism of excitation-contraction (E-C) coupling. In the ...
Pulsed local-field fluorescence microscopy: a new approach for measuring cellular ...
Pflugers Archiv : European Journal of Physiology (2003)
In cardiac research, single-cell experimental models have been extensively used to study the molecular mechanisms of intracellular Ca(2+) homeostasis. The ...
Conference proceedings, presentations, posters, abstracts, and lectures given by Dr. Carlos A. Villalba-Galea.