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The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019.
J Immunother Cancer
  • Paolo A Ascierto
  • Carlo Bifulco, Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Portland Medical Center, Portland, OR
  • Jerome Galon
  • Claus Garbe
  • Samir N Khleif
  • Jennifer McQuade
  • Kunle Odunsi
  • Hideho Okada
  • Chrystal M Paulos
  • Sergio A Quezada
  • Hussein A Tawbi
  • John Timmerman
  • Giorgio Trinchieri
  • Lisa H Butterfield
  • Igor Puzanov
Document Type
Publication Date
  • CTLA-4 antigen,
  • chimeric antigen,
  • cytotoxicity,
  • immunologic,
  • immunotherapy,
  • receptors

As part of the 2019 Immunotherapy Bridge congress (December 4-5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor T cell therapy in solid tumors, whether the Immunoscore should be more widely used in clinical practice, whether antibody-dependent cellular cytotoxicity is important in the mode of action of anticytotoxic T-lymphocyte-associated protein 4 antibodies, whether the brain is immunologically unique or just another organ, the role of microbiome versus nutrition in affecting responses to immunotherapy, and whether chemotherapy is immunostimulatory or immunosuppressive. Discussion of these important topics are summarized in this report.

Clinical Institute
Earle A. Chiles Research Institute
Citation Information
Paolo A Ascierto, Carlo Bifulco, Jerome Galon, Claus Garbe, et al.. "The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019." J Immunother Cancer (2020)
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