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Short report: Diagnostic testing for hemorrhagic fevers in Pakistan: 2007-2013.
The American journal of tropical medicine and hygiene.
  • Zahra Hasan, Agha Khan University
  • Barry Atkinson, Aga Khan University
  • Bushra Jamil, Aga Khan University
  • Azra Samreen, Aga Khan University
  • Lamia Altaf, Aga Khan University
  • Roger Hewson, Aga Khan University
Publication Date
12-1-2014
Document Type
Report
Disciplines
Abstract
Crimean-Congo hemorrhagic fever virus (CCHFV) and dengue virus (DENV) are endemic to Pakistan. Patients presenting with symptoms of fever, bleeding, and rash cannot be distinguished without appropriate testing. We report data on 354 samples tested for CCHFV at The AgaKhan University Hospital in Pakistan between 2007 and 2013. All samples were tested for the presence of CCHFV RNA. Some samples were also tested for DENV RNA, NS-1 antigen, and/or reactive immunoglobulin M antibodies. Of 354 clinical specimens screened for CCHFV, 52 specimens were positive, with 24 cases in 2013 alone. Most cases were from Sindh and Baluchistan, which border other CCHFV-endemic regions: Iran and Afghanistan. Among CCHFV-negative samples, 168 samples were tested for DENV, and 36% of these samples were found to be DENV-positive. Rapid differentiation of CCHFV and DENV can prevent nosocomial transmission and result in time and cost savings for patients and healthcare workers.
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Short-Reports.

Citation Information
Zahra Hasan, Barry Atkinson, Bushra Jamil, Azra Samreen, et al.. "Short report: Diagnostic testing for hemorrhagic fevers in Pakistan: 2007-2013." The American journal of tropical medicine and hygiene. Vol. 91 Iss. 6 (2014) p. 1243 - 1246
Available at: http://works.bepress.com/bushra_jamil/63/