"Tricyclic Antidepressant Toxicity Treated With Massive Sodium Bicarbonate" by Kathleen E Kane, MD

Selected Works of Bryan G. Kane, MD

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Tricyclic Antidepressant Toxicity Treated With Massive Sodium Bicarbonate

The American Journal Of Emergency Medicine

Kathleen E Kane, MD, Lehigh Valley Health Network
Bryan G Kane, MD, Lehigh Valley Health Network
Jessica E Pierog, DO, Lehigh Valley Health Network
J Ward Donovan, MD
Tracey Helmick, RN

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Publication/Presentation Date

11-1-2009

Abstract

Tricyclic antidepressant (TCA) morbitity is primarily due to cardiac arrhythmias and hypotension, which become more refractory to treatment as acidosis progresses (Ann Emerg Med. 1985;14:1-9; Clin Toxicol. 2007;45:203-233; Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's toxicologic emergencies. 8th ed. McGraw-Hill Companies, Inc, 2006). Early recognition and aggressive treatment are necessary for patient survival.

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PubMedID

19931778

Document Type

Article

Citation Information

Pierog, J. E., Kane, K. E., Kane, B. G., Donovan, J. W., & Helmick, T. (2009). Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. The American Journal Of Emergency Medicine, 27(9), 1168.e3-7. doi:10.1016/j.ajem.2008.11.026.