SelectedWorks - Brian B. Brennan

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Selected Works of Brian B. Brennan

Associate Professor of Chemistry

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About Brian B. Brennan

Present	Assistant Professor of Chemistry, Illinois Wesleyan University
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Chemistry

Chemistry and Chemical Biology

NIH Academic Research Enhancement Award

CNS C205C
Illinois Wesleyan University
Bloomington, IL 61702-2900
309-556-3972

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Articles (5)

Article

A Discovery-Oriented Approach to Solid-Phase Peptide Synthesis

Journal of Chemical Education (2012)

Brian B. Brennan, Matthew R. Bockman and Christopher J. Miedema

In this discovery-oriented laboratory experiment, students use solid-phase synthesis techniques to construct a dipeptide containing an unknown amino acid. Following ...

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Article

Amphipathic Small Molecules Mimic the Binding Mode and Function of ...

ACS Chemical Biology (2009)

Brian B. Brennan, Sara J. Buhrlage, Caleb A. Bates, Steven P. Rowe, et al.

Small molecules that reconstitute the binding mode(s) of a protein and in doing so elicit a programmed functional response offer ...

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Article

Unraveling the Mechanism of a Potent Transcriptional Activator

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Brian B. Brennan, Zhen Lu, Steven P. Rowe, Sarah E. Davis, et al.

Despite their enormous potential as novel research tools and therapeutic agents, artificial transcription factors (ATFs) that up-regulate transcription robustly in ...

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Article

Stereochemical Promiscuity in Artificial Transcriptional Activators

Journal of the American Chemical Society (2005)

Brian B. Brennan, Sara J. Buhrlage, Aaron R. Minter and Anna K. Mapp

Small molecule replacements of transcriptional activation domains are highly desirable targets due to their utility as mechanistic tools and their ...

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Article

Targeting the Transcriptional Machinery with Unique Artificial Transcriptional Activators

Journal of the American Chemical Society (2003)

Brian B. Brennan, Zhiqian Wu, Garrette Belanger, Jenifer K. Lum, et al.

The link between a growing number of human diseases and misregulation of gene expression has spurred intense interest in artificial ...

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Other

A Novel Peptide Inhibitor of the Polymerization of Deoxygenated Sickle ...

(2015)

Brian B. Brennan and Timothy Broederdorf, '15

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Other

Possible New Therapeutic Treatment for Sickle Cell Disease

(2014)

Brian B. Brennan and Ben Becker, '14

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Other

The Development of A Novel Therapeutic for the Treatment of ...

(2012)

Brian B. Brennan and Cody Wynn, '14

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Other

Fluorescent Studies of Peptidic Hemoglobin Binding Ligands

(2011)

Brian B. Brennan and Chris Brackett, '11

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Other

Solid-Phase Peptide Synthesis

(2011)

Brian B. Brennan and Elisabeth Sonta, '13

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Other

The Synthesis of a Cyclic Peptide Library for the Discovery ...

(2010)

Brian B. Brennan and Jeremy Henle, '11

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Other

Homologation of α-Amino Acids to β-Amino Acids via a Modified ...

(2009)

Brian B. Brennan and James Carolan, '10

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Other

Novel Therapeutics in the Treatment of Sickle Cell Disease: Expression ...

(2009)

Brian B. Brennan and Susan Zhong, '11

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Other

The Development of a Novel Therapeutic for the Treatment of ...

(2009)

Brian B. Brennan and Steven Sturlis, '10

Link

Other

The Synthesis and Characterization of a Peptide Hemoglobin Ligand

(2009)

Brian B. Brennan and Chris Brackett, '11

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Other

The Synthesis of a Peptoid for Use as a Novel ...

(2009)

Brian B. Brennan and Michael Chiodo, '11

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Other

Utilizing Phage Display to Identify Novel Peptides that Bind to ...

(2009)

Brian B. Brennan and Chris Betzle, '10

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Other

Utilizing Phage Display to Identify Novel Peptides that Bind to ...

(2009)

Brian B. Brennan and Chris Betzle, '10

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Other

The Development of Novel Therapeutics for Sickle-Cell Disease

(2008)

Brian B. Brennan, Sara Costello, '10 and Steven Sturlis, '10

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Other

The Expression of Recombinant Hemoglobin in Escherichia Coli

(2008)

Brian B. Brennan, Christopher Miedema, '10 and Evan Mason, '10

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Articles (5)

Faculty Advisor of Undergraduate Research (15)