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Cadherin2 (N-Cadherin) Plays An Essential Role in Zebrafish Cardiovascular Development
BMC Developmental Biology
  • Brian Bagatto, University of Akron Main Campus
  • Jessie Francl, Kent State University - Kent Campus
  • Bei Liu, Kent State University - Kent Campus
  • Qin Liu, University of Akron Main Campus
Document Type
Article
Publication Date
5-23-2006
Disciplines
Abstract
Background: Cadherins are cell surface adhesion molecules that play important roles in development of vertebrate tissues and organs. We studied cadherin2 expression in developing zebrafish heart using in situ hybridization and immunocytochemical methods, and we found that cadherin2 was strongly expressed by the myocardium of the embryonic zebrafish. To gain insight into cadherin2 role in the formation and function of the heart, we analyzed cardiac differentiation and performance in a cadherin2 mutant, glass onion (glo).
Required Publisher's Statement

© 2007 Kramer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Comments

© 2007 Kramer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citation Information
Brian Bagatto, Jessie Francl, Bei Liu and Qin Liu. "Cadherin2 (N-Cadherin) Plays An Essential Role in Zebrafish Cardiovascular Development" BMC Developmental Biology Vol. 6 Iss. 23 (2006)
Available at: http://works.bepress.com/brian_bagatto/2/