Pappal RD, Roberts BW, Winkler W, et alAwareness and bispectral index (BIS) monitoring in mechanically ventilated patients in the emergency department and intensive care unit: a systematic review protocol. BMJ Open 2020;10:e034673. doi: 10.1136/bmjopen-2019-034673 http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. This article was published in BMJ Open following peer review and can also be viewed on the journal’s website at http://bmjopen.bmj.com.