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Article
Ageotypes: Distinct Biomolecular Trajectories in Human Aging.
Trends in pharmacological sciences
  • Brian D. Piening, Molecular Genomics Laboratory, Providence Portland Medical Center, Portland, OR; Earle A. Chiles Research Institute, Robert W. Franz Cancer Research Center, Providence Portland Cancer Center, Portland, OR.
  • Jennifer Lovejoy, Institute for Systems Biology, Seattle, WA, USA
  • John C Earls, Institute for Systems Biology, Seattle, WA, USA
Document Type
Article
Publication Date
3-16-2020
Keywords
  • gerontology,
  • multi-omics,
  • genomics
Abstract

Many studies have demonstrated that biological age (BA) varies significantly among individuals of similar chronological age. A recent study by Ahadi et al. used longitudinal and deep multi-omic profiling to identify individuals with distinct BA phenotypes or 'ageotypes'. These ageotypes open new avenues to creating diagnostic and treatment strategies that may slow the aging process based on the unique biochemistry of each individual.

Clinical Institute
Cancer
Specialty
Earle A. Chiles Research Institute
Specialty
Institute for Systems Biology
Citation Information
Brian D. Piening, Jennifer Lovejoy and John C Earls. "Ageotypes: Distinct Biomolecular Trajectories in Human Aging." Trends in pharmacological sciences (2020)
Available at: http://works.bepress.com/brian-piening/42/