Skip to main content
Article
Tri-comparison of Laparoscopic Nissen, Hill, and Nissen-Hill Hybrid Repairs for Uncomplicated Gastroesophageal Reflux Disease.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • Andreas M Schneider, Division of Thoracic Surgery, Swedish Cancer Institute and Medical Center
  • Ralph W Aye, Division of Thoracic Surgery, Swedish Medical Center and Cancer Institute, Seattle, Washington
  • Candice Wilshire, Division of Thoracic Surgery and Interventional Pulmonology, Swedish Cancer Institute, Seattle, Wash
  • Alexander S Farivar, Division of Thoracic Surgery, Swedish Medical Center and Cancer Institute, Seattle, Washington
  • Brian Louie, Division of Thoracic Surgery, Swedish Medical Center and Cancer Institute, Seattle, Washington
Document Type
Article
Publication Date
3-1-2017
Keywords
  • Adult,
  • Esophageal pH Monitoring,
  • Female,
  • Fundoplication,
  • Gastroesophageal Reflux,
  • Humans,
  • Hydrogen-Ion Concentration,
  • Laparoscopy,
  • Male,
  • Manometry,
  • Middle Aged,
  • Proton Pump Inhibitors,
  • Quality of Life,
  • Randomized Controlled Trials as Topic,
  • Recurrence,
  • Reoperation,
  • Retrospective Studies,
  • Treatment Outcome
Disciplines
Abstract

BACKGROUND: A randomized controlled trial (RCT) showed that laparoscopic Nissen fundoplication (LNF) and Hill (LHR) repairs are equivalent in treating uncomplicated GERD. We combined both repairs to create a laparoscopic Nissen-Hill Hybrid repair (HYB). The purpose of this study is to compare clinical and objective outcomes of a matched group of HYB to the two cohorts of the RCT.

METHODS: A retrospective analysis of prospectively collected data from the RCT and a prospectively collected data base was performed. Data were collected preoperatively, postoperatively short-term (ST) at 6 weeks and mid-term (MT) at 6-12 months. Evaluation was standardized according to the RCT and included three quality of life metrics (QOLRAD, GERD-HRQL, Dysphagia), endoscopy, manometry, pH testing, and barium swallow.

RESULTS: There were 51 HYB, 46 LNF, and 56 LHR patients. Age, BMI, follow-up, and gender were comparable. QOLRAD, HRQL, PPI use, DeMeester scores, and pH% timeLNF, four LHR, and two HYB patients. Reoperations were performed in three LHR, two LNF, and zero HYB patients.

CONCLUSION: Tri-comparison shows that HYB is a promising alternative to LHR and LNF. Side effects were not increased and there were fewer reoperations for failure.

Clinical Institute
Digestive Health
Department
Gastroenterology
Department
Surgery
Citation Information
Andreas M Schneider, Ralph W Aye, Candice Wilshire, Alexander S Farivar, et al.. "Tri-comparison of Laparoscopic Nissen, Hill, and Nissen-Hill Hybrid Repairs for Uncomplicated Gastroesophageal Reflux Disease." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2017)
Available at: http://works.bepress.com/brian-louie/217/