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Article
The relationship between adiposity and stature in prepubertal children with celiac disease
Endocrinology/Diabetes
  • Benjamin U. Nwosu, University of Massachusetts Medical School
  • Rachel I. Snook, University of Massachusetts Medical School `
  • Louise S. Maranda, University of Massachusetts Medical School
UMMS Affiliation
Department of Pediatrics
Date
10-1-2013
Document Type
Article
Medical Subject Headings
Celiac Disease; Adiposity; Obesity; Body Mass Index; Body Height; Child
Abstract
Background and Aim: The pathogenesis of short stature in celiac disease (CD) is unknown. Obese children are generally taller than their non-obese peers; however, the role of adiposity on stature in CD is unclear. Our aim was to determine the association between adiposity and stature in CD. Subjects and methods: We compared the anthropometric characteristics of prepubertal children of ages 3-12 years, with biopsy-proven CD (n=40) and who were not on gluten-free diet, to same aged, prepubertal non-CD children (n=50). Body mass index (BMI) was calculated using the formula weight/height2. Sex-adjusted midparental target height (MPTH) standard deviation score (SDS) was calculated using National Children Health Statistics data for 18-year-old adults. Data were expressed as mean±standard deviation. Results: CD subjects had significantly lower BMI SDS than controls (0.61±1.22 vs. 1.28±1.60, p=0.027) but were not significantly shorter than the controls (-0.05±1.21 vs. 0.21±1.71, p=0.41). When the patients were subdivided into the normal-weight and overweight/obese groups, the normal-weight CD patients were of similar height as the normal-weight controls (p=0.76) but were significantly shorter than both the overweight/obese controls (p=0.003). The MPTH SDS did not differ between the groups. Conclusions: Overweight/obese prepubertal children with CD were taller than both their normal-weight CD peers and the normal-weight controls, but were of similar height as the overweight/obese control subjects.
Comments

Citation: Nwosu BU, Snook RI, Maranda L. The relationship between adiposity and stature in prepubertal children with celiac disease. J Pediatr Endocrinol Metab. 2013;26(9-10):819-24. doi: 10.1515/jpem-2012-0312. Link to article on publisher's site

The final publication is available at www.degruyter.com. Publisher PDF posted as allowed by the publisher's author rights policy at http://www.degruyter.com/dg/page/308/copyright-agreement.

Related Resources
Link to article in PubMed
PubMed ID
23729610
Citation Information
Benjamin U. Nwosu, Rachel I. Snook and Louise S. Maranda. "The relationship between adiposity and stature in prepubertal children with celiac disease" Vol. 26 Iss. 9-10 (2013) ISSN: 0334-018X
Available at: http://works.bepress.com/benjamin_nwosu/23/