Evaluating amyloid beta (Aβ) 1-40 degradation by capillary electrophoresis.Methods in Molecular Biology (2013)
Here, we describe a capillary electrophoresis method for evaluating proteolysis of the amyloid beta peptide (Aβ) 1-40. This method is suitable for kinetic studies, demands little specialized equipment, and consumes only small quantities of a commercially available substrate whose physiological accumulation is thought to underlie the development of Alzheimer's disease.
- Amyloid beta peptides,
- insulin-degrading enzyme,
- capillary electrophoresis
Citation InformationBenjamin J. Alper and Walter K. Schmidt. "Evaluating amyloid beta (Aβ) 1-40 degradation by capillary electrophoresis." Methods in Molecular Biology Vol. 984 (2013) p. 263 - 273
Available at: http://works.bepress.com/benjamin_alper/20/